绿色化学合成方法、林源活性物化学合成与修饰、林源药物合成
015/04-至今，南京林业大学，化学工程学院，教授
2012/1 – 2015/01，德国马普煤炭所，博士后，导师：诺贝尔化学奖得主Benjamin List
2011/4 -2011/11，美国加州大学圣芭芭拉分校，化学，助理研究员，合作导师：Bruce H. Lipshutz
2006/6 - 2011/3，美国加州大学圣芭芭拉分校，有机化学，博士，导师：Bruce H. Lipshutz
2003/9 - 2006/3，浙江大学，有机化学，硕士，导师：潘远江
1999/9 - 2003/6，浙江大学，化学，学士，导师：潘远江
1. YingyinZhang, Qingyuan Feng, Yu Zheng, Yanju Lu, Saihu Liao, and Shenlin Huang*Radical Hydro-Fluorosulfonylation of Propargylic Alcohols via ElectronDonor–Acceptor Photoactivation. Org. Lett. 2024, 26, 1410–1415.
2. TianyuHe, Chaoqiang Liang, Haoyuan Cheng, Shuai Shi, and Shenlin Huang* CathodicallyCoupled Electrolysis to Access Biheteroaryls. Org. Lett. 2024, 26,607–612.
3. Peng-ChengXu, Shencheng Qian, Xiangtai Meng, Yu Zheng, and Shenlin Huang* ElectrochemicalRing-Opening of Cyclopropylamides with Alcohols toward the Synthesis of1,3-Oxazines. Org. Lett. 2024, 26, 607–612.
4. YuZheng,* Wenguang Lu, Tianting Ma, Shenlin Huang* Recent advances inphotochemical and electrochemical strategies for the synthesis of sulfonylfluorides. Org. Chem. Front. 2024, 11, 217-235.
5. QingyuanFeng, Tianyu He, Shencheng Qian, Peng Xu, Saihu Liao & Shenlin Huang Electroreductivehydroxy fluorosulfonylation of alkenes. Nat. Commun. 2023,14,8278.
6. Xu-MinCai,* Yuting Lin, Jianyu Zhang, Ying Li, Zhenguo Tang, Xuedan Zhang, Ying Jia,Wenjin Wang, Shenlin Huang,* Parvej Alam, Zheng Zhao,* Ben Zhong Tang* Chromene-basedBioAIEgens: ‘in-water’ synthesis, regiostructure-dependent fluorescence andER-specific imaging. Natl. Sci. Rev. 2023, 10, nwad233.
7. YuZheng,* Wenguang Lu, Tianting Ma, Shenlin Huang* SO2ClF-PromotedChlorooxidation of Tryptamine Derivatives: Synthesis of 3,3-DisubstitutedOxindoles. Asian J. Org. Chem. 2024, 13, e2023005.
8. Wei-MinHe,* Shenlin Huang* Water for synthesis and extraction (2023). Curr. Opin. Green. Sustain. Chem. 2023,43, 100858.
9. MeizhongTang, Ye Wang, Shenlin Huang*, and Lan-Gui Xie* Synthesis of ArylThioalkynes Enabled by Electrophilic Sulfenylation of Alkynes and the FollowingElimination. J. Org. Chem. 2023, 88, 15466–15472.
10. QiuyueWang, Xiangtai Meng, Meiling Sun, Zhi Wang, Jiao He, Shenlin Huang, Lin Huang*Evaluation of the Antifungal Activity of Polysubstituted Cyclic 1,2-Diketonesagainst Colletotrichum gloeosporioides. Forests 2023, 14, 1172.
11. XueyanZhao, Dengfeng Chen, Shengzhen Zhu, Jinyue Luo, Saihu Liao, Binnan Zheng, Shenlin Huang* Fluorosulfonylvinylationof Unactivated C(sp3)–H via Electron Donor–Acceptor Photoactivation.Org. Lett. 2023, 25, 3109-3113.
12. ShuaiShi, Xueyan Zhao, Dengfeng Chen, Jinyue Luo, Saihu Liao, Shenlin Huang* C(sp3)–Hfluorosulfonylvinylation/aza-Michael addition approach to FSO2-functionalizedtetrahydropyridines. Org. Chem. Front.2023, 10, 3805-3810.
13. YuZheng,* Tianting Ma, Bingcong Liu, ShenlinHuang* SO2ClF-promoted chlorination-oxidation of2-methylindoles: a one-step synthetic method to access 2,3-difunctionalizedindoles. Org. Chem. Front. 2023, 10, 4100-4104.
14. MeizhongTang, Ye-Xin Wang, Shenlin Huang,*Lan-Gui Xie* Regio- and stereoselective oxidative conversion of alkynes tosulfenylated α,β-unsaturated carbonyls. Org.Chem. Front. 2023, 10, 2416-2421.
15. TiantingMa, Yu Zheng,* Shenlin Huang* SO2ClF:A Reagent for Controllable Chlorination and Chlorooxidation of SimpleUnprotected Indoles. J. Org. Chem. 2023, 88, 4839-4847.
16. TianyuHe, Chaoqiang Liang, Shenlin Huang* Cobalt-electrocatalyticC–H hydroxyalkylation of N-heteroarenes with trifluoromethyl ketones. Chem. Sci. 2023, 14, 143-148.
17. QingyuanFeng, Yamin Wang, Binnan Zheng, ShenlinHuang* Electrochemical Oxidative Cleavage of Alkynes to Carboxylic Acids. Org. Lett. 2023, 25, 293-297.
18. JiajinXia, Baolong Zhu, Qiuling Wan, Yinghua Yu,* Shenlin Huang,* Jian Zhang, Xueliang Huang* Gold-Catalyzed CascadeReaction of Diynamides with Allylic Alcohols: A Versatile Platform toAllenamide, 2-Aminofuran and Bridged [2.2.2]Octadiene Derivatives. Chem. Eur. J. 2023, 29, e202300826.
19. ShenchengQian, Pengcheng Xu, Yu Zheng, ShenlinHuang* Electrochemical oxythiocyanation of ortho-olefinic amides: Access todiverse thiocyanated benzoxazines.Tetrahedron Let. 2023, 116, 154341.
20. PingJiang, Rui Liu, Xiangtai Meng, Binnan Zheng, Yu Zheng, Shenlin Huang* Electrochemical Synthesis of 3-Sulfonylindoles viaAnnulation of o-Alkynylanilines with Sodium Sulfinates. Synthesis 2023, 55, 2959-2968. (Invited)
21. YuZheng, Shencheng Qian, Pengcheng Xu, Binnan Zheng, Shenlin Huang* Electrochemical Oxidative Thiocyanosulfonylation ofAryl Acetylenes. Chin. J. Org. Chem. 2022, 42, 4275. (Invited)
22. YuZheng, Shencheng Qian, Pengcheng Xu, Tianting Ma, Shenlin Huang* BF3·Et2O PromotedInverse-Electron-Demand Oxa-Diels-Alder Reaction of Alkylidene Isoxazol-5-oneswith Unactivated Alkenes. Adv. Synth.Catal. 2022, 364, 3800.
23. MeizhongTang, Yongjiao Wei, Shenlin Huang,* Lan-GuiXie* Regio- and Stereoselective Synthesis of β?Methylthio Vinyl Triflates. Org. Lett. 2022, 24, 7026.
24. YuanyuanFu, Shengzhen Zhu, Xueyan Zhao, ShenlinHuang* Photoredox-catalyzed coupling of acyl oxime acetates withthiophenols to give arylthioesters in water at room temperature. Green Chem. 2022, 24, 6849.
25. SichangWang, Ming Yuan, Qunzheng Zhang, ShenlinHuang* Recent progress in copper nanocatalysis for sustainabletransformations. Curr. Opin. Green.Sustain. Chem. 2022, 38, 100698.
26. QingyuanFeng, Yuanyuan Fu, Yu Zheng, Saihu Liao, ShenlinHuang* Electrochemical Synthesis of β?Keto Sulfonyl Fluorides via Radical Fluorosulfonylationof Vinyl Triflates. Org. Lett. 2022, 24, 3702.
27. XiangtaiMeng, Hehua Xu, Rui Liu, Yu Zheng, ShenlinHuang* Electrochemical triamination of alkynes: controllable synthesis offunctionalized indolines and indoles. GreenChem. 2022, 24, 4754.
28. JinliWang, Meizhong Tang, Weijin Gu, ShenlinHuang, and Lan-Gui Xie* Synthesis of Pyrrole via Formal Cycloaddition ofAllyl Ketone and Amine under Metal-Free Conditions. J. Org. Chem. 2022, 87, 12482.
29. XiangtaiMeng, Hehua Xu, Yu Zheng, Jinyue Luo, ShenlinHuang* Electrochemical Decarboxylative Oxygenation of Carboxylic Acids. ACS Sustainable Chem. Eng. 2022, 10, 5067. (Invited)
30. YuanHuang, Xueyan Zhao, Dengfeng Chen, Yu Zheng, Jinyue Luo, Shenlin Huang* Access to Sulfocoumarins by Three-Component Reactionof β-Keto Sulfonyl Fluorides, Arynes, and DMF. Eur. J. Org. Chem. 2022,e202200715.
31. PingJiang, Yaming Wang, Dengfeng Chen, Yu Zheng,* Shenlin Huang* Synthesis of 3-Acyl-Isoxazoles via Radical 5-endotrig Cyclization of β,γ-Unsaturated Ketones with NaNO2. Eur. J. Org. Chem. 2022, e202101411.
32. YingyinZhang, Baolong Zhu, Yu Zheng, ShenlinHuang? A rosin-based surfactant enabling cross-couplings ofvinyl dibromides with sulfonamides in water. J. Organomet. Chem. 2022,122321. (Invited)
33. YuanHuang, Dengfeng Chen, Yu Zheng,* ShenlinHuang* Synthesis of 3-Sulfonyl Indenones via Copper-Catalyzed Redox-NeutralCoupling Reaction. ChemistrySelect 2022, 7, e20210434.
34. DengfengChen, Tianyu He, Yongcan Jin,* ShenlinHuang* Electrooxidative Dearomatization to Spiroisoxazolines: Applicationto Total Synthesis of Xanthoisoxazoline B. Adv. Syn.Catal. 2022, 364, 286.
35. HehuaXu, Xiangtai Meng, Yu Zheng, Jinyue Luo,* ShenlinHuang* Electrochemical Annulations of o-Alkynylanilines for Synthesis of3-Iodoindoles. Chin. J. Org. Chem. 2021, 41, 4696. (Invited)
36. DengfengChen, Xingliang Nie, Qingyuan Feng, Yingyin Zhang, Yiheng Wang, Qiuyue Wang,Lin Huang, Shenlin Huang,* SaihuLiao* Electrochemical Oxo-Fluorosulfonylation of Alkynes under Air: FacileAccess to β-Keto Sulfonyl Fluorides. Angew.Chem. Int. Ed. 2021, 60, 27271.
37. YuanyuanFu, Xueyan Zhao, Dengfeng Chen, Jinyue Luo, Shenlin Huang* Cu-catalyzed coupling of indanone oxime acetateswith thiols to 2,3-difunctionalized indenones. Chem. Commun. 2021, 57, 10719.
38. TianyuHe, Dengfeng Chen, Shencheng Qian, Yu Zheng, Shenlin Huang* Selective C–C Bond Cleavage of Cycloalkanones byNaNO2/HCl. Org. Lett. 2021, 23, 6525.
39. XiangtaiMeng, Dengfeng Chen, Rui Liu, Ping Jiang, ShenlinHuang* Synthesis of 2-(Cyanomethyl)benzoic Esters via Carbon–Carbon BondCleavage of Indanones. J. Org. Chem. 2021, 86, 10852.
40. Xu-MinCai, Yuting Lin, Ying Li, Zaiyu Wang, Xueqian Zhao, Shenlin Huang,* Zheng Zhao,* Ben Zhong Tang* BioAIEgens Derivedfrom Rosin: How Does Molecular Motion Affect Their Photophysical Processes inSolid State? Nat. Commun. 2021, 12, 1773.
41. MeizhongTang, Shuxiong Han, Shenglan Huang, ShenlinHuang, Lan-Gui Xie* Carbosulfenylation of Alkenes with Organozinc Reagentsand Dimethyl(methylthio)sulfonium Trifluoromethanesulfonate. Org. Lett. 2020, 22, 9729.
42. Xiangtai Meng, Hehua Xu, Xiaoji Cao, Xu-Min Cai,Jinyue Luo, Fei Wang, Shenlin Huang*Electrochemically EnabledSulfonylation of Alkynes with Sodium Sulfinates. Org. Lett. 2020, 22, 6827.
43. Dengfeng Chen, Yaming Wang, Xu-Min Cai, Xiaoji Cao,Ping Jiang, Fei Wang, Shenlin Huang*Synthesis of Spiroisoxazolines via TEMPO/NaNO2-Catalyzed AerobicOxidative Dearomatization. Org. Lett. 2020, 22, 6847.
44. ChenjingLiu, Dengfeng Chen, Yuanyuan Fu, Fei Wang, Jinyue Luo*, Shenlin Huang* Sulfoxide Reduction/C(sp3)–S Metathesis Cascade inIonic Liquid. Org. Lett. 2020, 22, 5701.
45. DengfengChen, Tianyu He, Yuan Huang, Jinyue Luo, Fei Wang, Shenlin Huang* Synthesis of Spiroisoxazolines via an Oximation/DearomatizationCascade under Air. Org. Lett. 2020, 22, 4429.
46. BaolongZhu, Lei Zhu, Jiajin Xia, Shenlin Huang,*Xueliang Huang*Gold-catalyzed cycloisomerization of enynamides: Regio- andstereoselective approach to tetracyclic spiroindolines. Tetrahedron 2020, 76, 131056.
47. ShengzhenZhu, Yu Zhang, Jinyue Luo, Fei Wang, Xiaoji Cao, Shenlin Huang*Temperature-controlledregioselective thiolation of 2-indolylmethanols under aqueous micellarconditions. Green Chem. 2020, 22, 657.
48. XiangtaiMeng, Yu Zhang, Jinyue Luo, Fei Wang, Xiaoji Cao, Shenlin Huang* Electrochemical Oxidative Oxydihalogenation ofAlkynes for the Synthesis of α,α-Dihaloketones. Org. Lett. 2020, 22, 1169.
49. TianxiaoXu, Tianpeng Cao, Qingyuan Feng, ShenlinHuang,* Saihu Liao* Metal-free dehydrosulfurization of thioamides tonitriles under visible light.Chem. Commun.2020, 56, 5151.
50. XiangtaiMeng, Dengfeng Chen, Xiaoji Cao, Jinyue Luo, Fei Wang, Shenlin Huang* Synthesis of polysubstituted cyclic1,2-diketonesenabled by iterative sulfoxide-mediated arylation. Chem. Commun. 2019, 55, 12495.
51. WenqianLina, Dengfeng Chen, Qiang Yong, Caoxing Huang,* Shenlin Huang*Improvingenzymatic hydrolysis of acid-pretreated bamboo residues using amphiphilicsurfactant derived from dehydroabietic acid. Bioresour. Technol. 2019,293, 122055.
52. DengfengChen, Yuanyuan Fu, Xiaoji Cao, Jinyue Luo, Fei Wang, Shenlin Huang* Metal-Free Cyclopropanol Ring Opening C(sp3)–C(sp2)Cross-Couplings with Aryl Sulfoxides. Org.Lett. 2019, 21,5600.
53. HengZhang, Yinghua Yu, Shenlin Huang,Xueliang Huang* Palladium-Catalyzed Cascade Reaction of o-Bromobenzaldehydes with N-Sulfonylhydrazones: An EfficientApproach to the Naphthalene Skeleton. Adv.Syn. Catal. 2019, 361, 1576.
54. YunqinYang, Xiangtai Meng, Baolong Zhu, Ying Jia, Xiaoji Cao, Shenlin Huang*AMicellar Catalysis Strategy for Amidation of Alkynyl Bromides: Synthesis ofYnamides in Water. Eur. J. Org. Chem.2019, 1166.
55. DengfengChen, Yuchen Zhang, Xingyu Pan, Fei Wang, ShenlinHuang* Oxidation of Tertiary Aromatic Alcohols to Ketones in Water. Adv. Syn. Catal. 2018, 360, 3607.
56. QingyuanFeng, Dengfeng Chen, Mei Hong, Fei Wang, ShenlinHuang* Phenyliodine(III) Bis(trifluoroacetate) (PIFA)-Mediated Synthesis ofAryl Sulfides in Water. J. Org. Chem.2018, 83, 7553.
57. XiaoChen, Xinfei Chen, Xu-Min Cai*, ShenlinHuang, Fei Wang* Cellulose Dissolution in a Mixed Solvent ofTetra(n?butyl)ammonium Hydroxide/Dimethyl Sulfoxide via Radical Reactions. ACS Sustainable Chem. Eng. 2018, 6, 2898.
58. TaoYuan, Shenlin Huang,Chun Cai, Guo-ping Lu* Metal-freeelectrophilic phosphination of electron-rich arenes, arenols and aromaticthiols with diarylphosphine oxides. Org.Biomol. Chem. 2018, 16, 30.
59. Dengfeng Chen, QingyuanFeng, Yunqin Yang, Xu-Min Cai, Fei Wang,Shenlin Huang* Metal-Free O–H/C–H Difunctionalization ofPhenols by o-HydroxyarylsulfoniumSalts in Water. Chem. Sci. 2017, 8,1601.
60. TakashiNishikata, Alexander R. Abela, ShenlinHuang, Bruce H. Lipshutz* Cationic Pd(II)-catalyzed C–HActivation/Cross-coupling Reactions at Room Temperature: Synthetic andMechanistic Studies. Beilstein J. Org.Chem. 2016, 12, 1040.
61. ShenlinHuang, Lisa K?tzner, Chandra Kanta De, Benjamin List*Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with ArylHydrazines Giving 1,4-Diketones. J. Am. Chem.Soc. 2015, 137, 3446.
62. BruceH. Lipshutz*, Shenlin Huang, WendyWen Yi Leong, Guofu Zhong, Nicholas A. Isley C–C Bond Formation viaCopper-Catalyzed Conjugate Addition Reactions to Enones in Water at RoomTemperature. J. Am. Chem. Soc. 2012, 134, 19985.
63. Shenlin Huang, Tue B. Petersen, BruceH. Lipshutz* Total Synthesis of (+)-Korupensamine B via an AtropselectiveIntermolecular Biaryl Coupling. J. Am.Chem. Soc. 2010, 132, 14021.
64. Shenlin Huang, Karl R. Voigtritter, JohnB. Unger, Bruce H. Lipshutz* Asymmetric CuH-Catalyzed 1,4-Reductions in Waterat Room Temperature. Synlett 2010, 2041.
65. TakashiNishikata, Alexander R. Abela, ShenlinHuang,Bruce H. Lipshutz*Cationic Palladium(II) Catalysis: C-H Activation/Suzuki-Miyaura Couplings atRoom Temperature. J. Am. Chem. Soc. 2010,132, 4978.
66. Ching-TienLee, Shenlin Huang, Bruce H. Lipshutz* Cu/C-Catalyzed, Tandem One-Pot DiazoTransfer-Click Reactions Adv. Syn. Catal.2009, 353, 3139.